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Aplastic anemia

Also called: Aplastic anemia

The bone marrow stops making enough blood cells, causing tiredness, infections, and bleeding.

TreatmentImmune therapy, stem cell transplant

Overview

In aplastic anemia, the bone marrow makes too few red cells, white cells, and platelets.

It can be caused by the immune system, some medicines, toxins, or viruses.

Symptoms

Common signs:

  • Tiredness, bruising, infections

Less common

  • Pale skin
  • Shortness of breath
  • Fever

When to get medical care

Call 911Fever or heavy bleeding.
Get care todayNew bruising.
See a doctor soonSymptoms that last or keep coming back.

Causes

Marrow failure.

Does it spread or run in families?

  • It isn't contagious. You can't catch it from someone else.

Diagnosis

Blood and marrow tests.

Treatment

Avoid infection.

Self-care

  • Handwashing
  • Wash hands often and avoid sick people
  • Use a soft toothbrush
  • Avoid contact sports
  • Avoid crowds

Prevention

To lower your risk or prevent problems:

  • Avoid benzene and toxic chemicals

Which doctor treats this

  • Start with your primary care provider (family doctor or internist).
  • They may send you to a hematologist (blood doctor).

Living with it

Support groups and helplines

Children, pregnancy, and older adults

  • Young adults and older adults: Most common.
  • Young adults: Most common.

Pregnancy and breastfeeding

  • If you're pregnant or planning to be, tell your prenatal provider about this condition.
  • Don't start or stop any medicine on your own. Some are safe in pregnancy and some need to be changed.
  • Ask before taking any pain reliever. The FDA advises avoiding ibuprofen and naproxen after 20 weeks unless your doctor says to.
  • Breastfeeding: Most medicines are fine, but ask. The NIH LactMed database lists what's known about each one.

Outlook

Treatable.

Stem cell transplant can cure it.

Getting ready for your visit

Bring a list of your symptoms and medicines.

What to bring

  • A list of your medicines and supplements
  • Notes on when symptoms started and what makes them better or worse

Questions to ask

  • What's causing my symptoms?
  • What treatment do you recommend?

Research studies

Research studies test new ways to find and treat health problems. Some are looking for volunteers. Talk with your doctor before joining one.

Search ClinicalTrials.gov for studies on Aplastic anemia

Sources

Last updated 2026-11-12.