Cassava poisoning (konzo)

Overview

Konzo causes permanent leg weakness that starts suddenly.

Proper processing of cassava removes the toxin.

Symptoms

Common signs:

• Sudden leg weakness

Less common

• Vomiting

When to get medical care

Causes

Cyanide in cassava.

Who is more likely to get it

• People in drought or famine areas: Higher risk
• Children and women: Most affected

Possible complications

• Permanent leg weakness: Konzo damage usually doesn't heal

Diagnosis

This is diagnosed in the emergency room or hospital.

The exam

A physical exam.

Tests

Tests, if needed:

• Exam:

Treatment

Emergency care is needed. While waiting for help:

Self-care

• Get emergency care
• Process cassava by soaking, drying, and cooking well

Prevention

To lower your risk or prevent problems:

• Proper cassava processing
• Varied diet

Which doctor treats this

• Emergency doctors treat it first, in the ER.
• Poison Control can help right away, any time: call 1-800-222-1222.

Living with it

Support groups and helplines

• Genetic and Rare Diseases Information Center (GARD): Free NIH information on rare diseases, including where to find experts and patient groups.
• National Organization for Rare Disorders (NORD): Patient groups, help finding care, and aid programs for rare diseases.

Back to school, work, or sports

• Recovery time varies. Ask your care team when you can drive, lift, work, and exercise.

Children, pregnancy, and older adults

• Children and women in affected areas: Highest risk.

For caregivers

• Go to visits when you can and take notes.
• Keep a list of medicines, allergies, and doctors in one place.
• Learn the warning signs that need fast care.
• Take breaks and ask for help. Caregivers need care too.

Outlook

Weakness usually stays but doesn't worsen.

Getting ready for your visit

Bring a list of your symptoms and medicines.

What to bring

• A list of your medicines and supplements
• Notes on when symptoms started and what makes them better or worse

Questions to ask

• What follow-up care do I need?
• How can I prevent this from happening again?

Research studies

Research studies test new ways to find and treat health problems. Some are looking for volunteers. Talk with your doctor before joining one.

Search ClinicalTrials.gov for studies on Cassava poisoning (konzo)