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Dyshidrotic eczema

Also called: Dyshidrotic eczema, pompholyx, itchy blisters on hands

Small, deep, very itchy blisters on the palms, fingers, and soles. Flares are linked to stress, sweat, and allergies.

WherePalms, sides of fingers, soles
TriggersStress, sweat, nickel, wet work
TreatmentSteroid creams, moisturizer

Overview

Blisters dry and peel in 2 to 3 weeks.

It often comes back.

Symptoms

Common signs:

  • Itchy blisters on the hands or feet
  • Tiny itchy blisters on the hands, fingers, or feet
  • Itching

Less common

  • Peeling
  • Cracks

When to get medical care

Call 911This isn't an emergency by itself. Call 911 for trouble breathing, chest pain, or fainting.
Get care todayPus, spreading redness, or fever.
See a doctor soonFlares that keep coming back.

Causes

Stress, sweat, allergies.

Does it spread or run in families?

  • It isn't contagious. You can't catch it from someone else.

Who is more likely to get it

  • Eczema
  • Allergies

Diagnosis

A clinician looks at the hands.

Questions you may be asked

  • Triggers, allergies

Tests

Tests, if needed:

  • Patch test: For allergies.

Treatment

Calm the skin.

Self-care

  • Use cool compresses
  • Moisturize often
  • Wear gloves for wet work
  • Use mild soap

Medicines

Medicines that may help:

MedicineHelps withGood to know
Steroid creams
FlaresPrescription.
Anti-itch
Itch

OwieClear doesn't give doses: follow the label or your healthcare professional. Medicine names here are examples, not a full list.

Prevention

To prevent flares:

  • Moisturize
  • Protect hands

Which doctor treats this

  • Start with your primary care provider (family doctor or internist).
  • They may send you to a dermatologist (skin doctor).

Living with it

  • Moisturize at least twice a day.
  • Use gentle, fragrance-free products.
  • Long-term illness can affect mood. Tell your doctor if you feel down or anxious.

Support groups and helplines

Back to school, work, or sports

  • Most people can keep working or going to school.
  • Ask about changes that help, like extra breaks or a flexible schedule. Workers may be covered by the ADA. Students may get a 504 plan.

Pregnancy and breastfeeding

  • If you're pregnant or planning to be, tell your prenatal provider about this condition.
  • Some skin medicines, like isotretinoin and retinoid creams, aren't safe in pregnancy.
  • Don't start or stop any medicine on your own. Some are safe in pregnancy and some need to be changed.
  • Ask before taking any pain reliever. The FDA advises avoiding ibuprofen and naproxen after 20 weeks unless your doctor says to.
  • Breastfeeding: Most medicines are fine, but ask. The NIH LactMed database lists what's known about each one.

For caregivers

  • Go to visits when you can and take notes.
  • Keep a list of medicines, allergies, and doctors in one place.
  • Learn the warning signs that need fast care.
  • Take breaks and ask for help. Caregivers need care too.

Outlook

Manageable.

Getting ready for your visit

Bring a list of your symptoms and medicines.

Questions to ask

  • Should I be patch tested?

Research studies

Research studies test new ways to find and treat health problems. Some are looking for volunteers. Talk with your doctor before joining one.

Search ClinicalTrials.gov for studies on Dyshidrotic eczema

Sources

Last updated 2026-11-12.