Erythema multiforme

Overview

The rash often starts on hands and feet as round spots with a dark center, like a target.

The minor form usually follows a cold sore outbreak and clears in 2 to 4 weeks.

Symptoms

Common signs:

• Target-shaped rash

Less common

• Mouth sores
• Itching
• Burning
• Fever

When to get medical care

Causes

Herpes, medicines.

Does it spread or run in families?

• It isn't contagious. You can't catch it from someone else.

Who is more likely to get it

• Young adults: Most common age
• People who get cold sores: The most common trigger

Possible complications

• Eye damage: Rare, if the eyes are involved

Diagnosis

A clinician asks about your symptoms and may order tests.

The exam

A physical exam.

Tests

Tests, if needed:

• Exam:

Treatment

Treatment depends on the cause and how severe it is.

Self-care

• Use cool compresses
• Rinse mouth sores with salt water
• Use mouth rinses for sores

Prevention

To lower your risk or prevent problems:

• Treat cold sores early

Which doctor treats this

• Start with your primary care provider (family doctor or internist).
• They may send you to a dermatologist (skin doctor).

Children, pregnancy, and older adults

• Young adults: Most common.

Pregnancy and breastfeeding

• If you're pregnant or planning to be, tell your prenatal provider about this condition.
• Don't start or stop any medicine on your own. Some are safe in pregnancy and some need to be changed.
• Ask before taking any pain reliever. The FDA advises avoiding ibuprofen and naproxen after 20 weeks unless your doctor says to.
• Breastfeeding: Most medicines are fine, but ask. The NIH LactMed database lists what's known about each one.

Outlook

Usually heals without scars.

Clears in 2 to 4 weeks.

Getting ready for your visit

Bring a list of your symptoms and medicines.

What to bring

• A list of your medicines and supplements
• Notes on when symptoms started and what makes them better or worse

Questions to ask

• What's causing this?
• What treatment do you recommend?

Research studies

Research studies test new ways to find and treat health problems. Some are looking for volunteers. Talk with your doctor before joining one.

Search ClinicalTrials.gov for studies on Erythema multiforme