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Gangrene

Also called: Gangrene, tissue death

Body tissue dies from lack of blood flow or infection, turning black, with pain or numbness.

RisksDiabetes, poor circulation

Overview

Dry gangrene comes from poor blood flow. Wet or gas gangrene comes from infection and spreads fast.

Symptoms

Common signs:

  • Black or green skin
  • Foul-smelling wound

Less common

  • Fever
  • Numbness

When to get medical care

Call 911Call 911 now for: black or green skin, foul-smelling wound.
Get care todayMilder symptoms that could be early signs.
See a doctor soonQuestions about lowering your risk.

Causes

No blood flow or infection.

Does it spread or run in families?

  • It usually doesn't spread from person to person.
  • People get it from: food or wounds.

Who is more likely to get it

  • Diabetes
  • Smoking

Possible complications

  • Sepsis: Infection spreading into the blood

Diagnosis

This is diagnosed in the emergency room or hospital.

The exam

A physical exam.

Tests

Tests, if needed:

  • Exam:

Treatment

Emergency care is needed. While waiting for help:

Self-care

  • Get emergency care

Prevention

To lower your risk or prevent problems:

  • Control blood sugar
  • Check feet daily

Which doctor treats this

  • Emergency doctors treat it first, in the ER.
  • They may send you to an infectious disease specialist, for hard-to-treat infections.

Back to school, work, or sports

  • Recovery time varies. Ask your care team when you can drive, lift, work, and exercise.

Children, pregnancy, and older adults

  • People with diabetes: Check feet daily.

Pregnancy and breastfeeding

  • If you're pregnant or planning to be, tell your prenatal provider about this condition.
  • Some infections can pass to the baby during pregnancy or birth. Tell your provider if you've been exposed.
  • Don't start or stop any medicine on your own. Some are safe in pregnancy and some need to be changed.
  • Ask before taking any pain reliever. The FDA advises avoiding ibuprofen and naproxen after 20 weeks unless your doctor says to.
  • Breastfeeding: Most medicines are fine, but ask. The NIH LactMed database lists what's known about each one.

For caregivers

  • Go to visits when you can and take notes.
  • Keep a list of medicines, allergies, and doctors in one place.
  • Learn the warning signs that need fast care.
  • Learn CPR. Many hospitals and the Red Cross offer classes.
  • Take breaks and ask for help. Caregivers need care too.

Outlook

Fast treatment can save limbs.

Fast care saves tissue.

Getting ready for your visit

Bring a list of your symptoms and medicines.

What to bring

  • A list of your medicines and supplements
  • Notes on when symptoms started and what makes them better or worse

Questions to ask

  • What follow-up care do I need?
  • How can I prevent this from happening again?

Research studies

Research studies test new ways to find and treat health problems. Some are looking for volunteers. Talk with your doctor before joining one.

Search ClinicalTrials.gov for studies on Gangrene

Sources

Last updated 2026-11-12.