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Guillain-Barré syndrome

Also called: Guillain-Barré syndrome, GBS

The immune system attacks nerves, often after an infection, causing tingling and weakness that start in the feet and spread upward over days. It's an emergency.

StartsDays to weeks after an infection
DangerBreathing weakness
TreatmentIVIG or plasma exchange

Overview

GBS often follows a stomach bug or respiratory infection.

Weakness peaks within 4 weeks, then slowly improves.

Symptoms

Common signs:

  • Weakness spreading up from the legs
  • Weakness or tingling spreading up from the feet

Less common

  • Tingling
  • Back pain
  • Trouble walking

When to get medical care

Call 911Trouble breathing, swallowing, or fast-spreading weakness: call 911.
Get care todayTingling and weakness in both legs.
See a doctor soonSymptoms that last or keep coming back.

Causes

Immune reaction after infection.

Does it spread or run in families?

  • It isn't contagious. You can't catch it from someone else.

Diagnosis

Hospital tests.

Tests

Tests, if needed:

  • Spinal tap:
  • Nerve tests:

Treatment

Get care fast.

Self-care

  • Follow rehab plans

Medicines

Medicines that may help:

MedicineHelps withGood to know
IVIG
GBS

OwieClear doesn't give doses: follow the label or your healthcare professional. Medicine names here are examples, not a full list.

Hospital care and rehab.

Which doctor treats this

  • Start with your primary care provider (family doctor or internist).
  • They may send you to a neurologist (brain and nerve doctor).

Living with it

Support groups and helplines

Children, pregnancy, and older adults

  • Adults: More common with age.

Pregnancy and breastfeeding

  • If you're pregnant or planning to be, tell your prenatal provider about this condition.
  • Don't start or stop any medicine on your own. Some are safe in pregnancy and some need to be changed.
  • Ask before taking any pain reliever. The FDA advises avoiding ibuprofen and naproxen after 20 weeks unless your doctor says to.
  • Breastfeeding: Most medicines are fine, but ask. The NIH LactMed database lists what's known about each one.

Outlook

Most recover over months.

Getting ready for your visit

Bring a list of your symptoms and medicines.

What to bring

  • A list of your medicines and supplements
  • Notes on when symptoms started and what makes them better or worse

Questions to ask

  • How long is recovery?

Research studies

Research studies test new ways to find and treat health problems. Some are looking for volunteers. Talk with your doctor before joining one.

Search ClinicalTrials.gov for studies on Guillain-Barré syndrome

Sources

Last updated 2026-11-12.