Overview
Fever and sore throat often come first, then mouth sores and the rash. Adults can catch it too.
Painful mouth sores can make children refuse to drink. Weeks later, fingernails sometimes peel; this is harmless.
Symptoms
Common signs:
- Mouth sores
- Rash on hands and feet
- Spots on the hands, feet, and in the mouth
Less common
- Fever
- Sore throat
- Fussiness
Look up a symptom: Fever
When to get medical care
Causes
Viruses spread by saliva, mucus, stool, and blister fluid.
Does it spread or run in families?
- Yes, it can spread from person to person.
- How it spreads: coughs, sneezes, saliva, blister fluid, or stool.
- Washing hands often and staying home when sick help protect others.
Who is more likely to get it
- Children under 5
- Daycare
Possible complications
Diagnosis
Diagnosis is based on how it looks.
Questions you may be asked
- Drinking and peeing
- Others sick at daycare
The exam
Checking the mouth, hands, and feet.
Treatment
Comfort care while it runs its course.
Self-care
- Offer cold drinks, popsicles, and soft, bland foods
- Avoid salty, spicy, or acidic foods
- Use pain or fever medicine
- Wash hands well, especially after diaper changes
- Don't pop blisters
Medicines
Medicines that may help:
| Medicine | Helps with | Good to know |
|---|---|---|
| Pain and fever relievers | Mouth pain and fever | No ibuprofen under 6 months; dose by weight. |
OwieClear doesn't give doses: follow the label or your healthcare professional. Medicine names here are examples, not a full list.
Prevention
To prevent spread:
- Handwashing
- Clean toys and surfaces
Which doctor treats this
- Start with your primary care provider (family doctor or internist).
Back to school, work, or sports
- Stay home while there's a fever or drooling from mouth sores.
Pregnancy and breastfeeding
- If you're pregnant or planning to be, tell your prenatal provider about this condition.
- Some infections can pass to the baby during pregnancy or birth. Tell your provider if you've been exposed.
- Don't start or stop any medicine on your own. Some are safe in pregnancy and some need to be changed.
- Ask before taking any pain reliever. The FDA advises avoiding ibuprofen and naproxen after 20 weeks unless your doctor says to.
- Breastfeeding: Most medicines are fine, but ask. The NIH LactMed database lists what's known about each one.
Outlook
Almost all children recover fully.
Myths and facts
Myth: Hand, foot, and mouth disease comes from animals.
Fact: It's different from the animal disease and only spreads between people.
Getting ready for your visit
Bring a list of your symptoms and medicines.
Questions to ask
- When can my child go back to daycare?
Research studies
Research studies test new ways to find and treat health problems. Some are looking for volunteers. Talk with your doctor before joining one.
Search ClinicalTrials.gov for studies on Hand, foot, and mouth disease
Sources
Last updated 2026-11-12.