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Leptospirosis

Also called: Leptospirosis

A bacterial infection from water or soil contaminated by animal urine, causing fever, headache, muscle pain, and red eyes. Severe cases affect the liver and kidneys.

ExposureFloodwater, lakes, rats
TreatmentAntibiotics

Overview

It's common after flooding and in people who swim in or work around fresh water.

Calf muscle pain and red eyes are classic signs.

Symptoms

Common signs:

  • Fever and muscle aches
  • Body aches

Less common

  • Red eyes
  • Yellow skin
  • Less urine

When to get medical care

Call 911Yellow skin, bleeding, or little urine.
Get care todayFever after floodwater exposure.
See a doctor soonSymptoms that last or keep coming back.

Causes

Leptospira bacteria.

Does it spread or run in families?

  • It usually doesn't spread from person to person.
  • People get it from: water or animal urine.

Who is more likely to get it

  • Floods
  • Farm work

Diagnosis

A clinician asks about your symptoms and may order tests.

The exam

A physical exam.

Tests

Tests, if needed:

  • Blood tests:

Treatment

Treatment depends on the cause and how severe it is.

Self-care

  • Rest and fluids
  • Take antibiotics

Medicines

Medicines that may help:

MedicineHelps withGood to know
Antibiotics
Infection

OwieClear doesn't give doses: follow the label or your healthcare professional. Medicine names here are examples, not a full list.

Prevention

To lower your risk or catch problems early:

  • Avoid wading in floodwater
  • Cover cuts

Which doctor treats this

  • Start with your primary care provider (family doctor or internist).
  • They may send you to an infectious disease specialist, for hard-to-treat infections.

Pregnancy and breastfeeding

  • If you're pregnant or planning to be, tell your prenatal provider about this condition.
  • Some infections can pass to the baby during pregnancy or birth. Tell your provider if you've been exposed.
  • Don't start or stop any medicine on your own. Some are safe in pregnancy and some need to be changed.
  • Ask before taking any pain reliever. The FDA advises avoiding ibuprofen and naproxen after 20 weeks unless your doctor says to.
  • Breastfeeding: Most medicines are fine, but ask. The NIH LactMed database lists what's known about each one.

Outlook

Most recover with treatment.

Getting ready for your visit

Bring a list of your symptoms and medicines.

What to bring

  • A list of your medicines and supplements
  • Notes on when symptoms started and what makes them better or worse

Questions to ask

  • What's causing this?
  • What treatment do you recommend?

Research studies

Research studies test new ways to find and treat health problems. Some are looking for volunteers. Talk with your doctor before joining one.

Search ClinicalTrials.gov for studies on Leptospirosis

Sources

Last updated 2026-11-12.