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Overactive parathyroid (hyperparathyroidism)

Also called: Hyperparathyroidism, overactive parathyroid, high calcium

The parathyroid glands make too much hormone, raising blood calcium. It can cause kidney stones, thin bones, tiredness, and low mood.

Often foundOn routine blood tests
CureSurgery to remove the gland

Overview

Many people have no symptoms.

Symptoms

Common signs:

  • High calcium on a test

Less common

  • Kidney stones
  • Bone pain
  • Tiredness

When to get medical care

Call 911Confusion or severe weakness.
Get care todayKidney stone pain.
See a doctor soonHigh calcium.

Causes

A benign gland growth.

Does it spread or run in families?

  • It isn't contagious. You can't catch it from someone else.

Who is more likely to get it

  • Women after menopause
  • Women after menopause: Most common
  • People who had neck radiation: Higher risk

Possible complications

Diagnosis

A clinician asks about your symptoms and may order tests.

The exam

A physical exam.

Tests

Tests, if needed:

  • Calcium and PTH tests:
  • Bone density:

Treatment

Treatment depends on the cause and how severe it is.

Self-care

  • Drink plenty of water
  • Stay active

Which doctor treats this

  • Start with your primary care provider (family doctor or internist).
  • They may send you to an endocrinologist (hormone doctor).

Living with it

  • Take thyroid pills the same way every day, often on an empty stomach.
  • Get blood tests as advised.
  • Long-term illness can affect mood. Tell your doctor if you feel down or anxious.

Support groups and helplines

Back to school, work, or sports

  • Most people can keep working or going to school.
  • Ask about changes that help, like extra breaks or a flexible schedule. Workers may be covered by the ADA. Students may get a 504 plan.

Children, pregnancy, and older adults

  • Adults over 50: Most common.
  • Women after menopause: Most common.

Pregnancy and breastfeeding

  • If you're pregnant or planning to be, tell your prenatal provider about this condition.
  • This condition needs closer checkups during pregnancy. Plan ahead with your doctor.
  • Don't start or stop any medicine on your own. Some are safe in pregnancy and some need to be changed.
  • Ask before taking any pain reliever. The FDA advises avoiding ibuprofen and naproxen after 20 weeks unless your doctor says to.
  • Breastfeeding: Most medicines are fine, but ask. The NIH LactMed database lists what's known about each one.

For caregivers

  • Go to visits when you can and take notes.
  • Keep a list of medicines, allergies, and doctors in one place.
  • Learn the warning signs that need fast care.
  • Take breaks and ask for help. Caregivers need care too.

Outlook

Surgery usually cures it.

Getting ready for your visit

Bring a list of your symptoms and medicines.

What to bring

  • A list of your medicines and supplements
  • Notes on when symptoms started and what makes them better or worse

Questions to ask

  • What's causing this?
  • What treatment do you recommend?
  • Do I need surgery?

Research studies

Research studies test new ways to find and treat health problems. Some are looking for volunteers. Talk with your doctor before joining one.

Search ClinicalTrials.gov for studies on Overactive parathyroid (hyperparathyroidism)

Sources

Last updated 2026-11-12.