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Pseudogout (CPPD)

Also called: Pseudogout, CPPD

Crystals in a joint cause sudden painful swelling, often in the knee or wrist, in older adults.

TreatmentNSAIDs, steroid shots, colchicine

Symptoms

Common signs:

  • Sudden painful swollen joint
  • Red, hot, swollen joint

Less common

  • Fever

When to get medical care

Call 911Hot joint with high fever.
Get care todaySudden joint swelling.
See a doctor soonSymptoms that last or keep coming back.

Causes

Calcium crystals.

Does it spread or run in families?

  • It isn't contagious. You can't catch it from someone else.

Who is more likely to get it

  • Over 60

Diagnosis

A clinician asks about your symptoms and may order tests.

The exam

A physical exam.

Tests

Tests, if needed:

  • Joint fluid test:

Treatment

Treatment depends on the cause and how severe it is.

Self-care

  • Rest
  • Ice

Medicines

Medicines that may help:

MedicineHelps withGood to know
Pain relievers
Pain and swellingAsk first if you have kidney, stomach, or heart problems.

OwieClear doesn't give doses: follow the label or your healthcare professional. Medicine names here are examples, not a full list.

Which doctor treats this

  • Start with your primary care provider (family doctor or internist).
  • They may send you to a rheumatologist (joint and immune system doctor).

Living with it

  • Stay active with walking, swimming, or biking.
  • Keep a healthy weight to ease joint strain.
  • Long-term illness can affect mood. Tell your doctor if you feel down or anxious.

Support groups and helplines

Back to school, work, or sports

  • Most people can keep working or going to school.
  • Ask about changes that help, like extra breaks or a flexible schedule. Workers may be covered by the ADA. Students may get a 504 plan.

Pregnancy and breastfeeding

  • If you're pregnant or planning to be, tell your prenatal provider about this condition.
  • Don't start or stop any medicine on your own. Some are safe in pregnancy and some need to be changed.
  • Ask before taking any pain reliever. The FDA advises avoiding ibuprofen and naproxen after 20 weeks unless your doctor says to.
  • Breastfeeding: Most medicines are fine, but ask. The NIH LactMed database lists what's known about each one.

For caregivers

  • Go to visits when you can and take notes.
  • Keep a list of medicines, allergies, and doctors in one place.
  • Learn the warning signs that need fast care.
  • Take breaks and ask for help. Caregivers need care too.

Outlook

Outlook depends on the cause; early care helps.

Getting ready for your visit

Bring a list of your symptoms and medicines.

What to bring

  • A list of your medicines and supplements
  • Notes on when symptoms started and what makes them better or worse

Questions to ask

  • What's causing this?
  • What treatment do you recommend?

Research studies

Research studies test new ways to find and treat health problems. Some are looking for volunteers. Talk with your doctor before joining one.

Search ClinicalTrials.gov for studies on Pseudogout (CPPD)

Sources

Last updated 2026-11-12.