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Sjögren's syndrome

Also called: Sjögren's syndrome, Sjogren's

An immune disease that attacks the glands that make tears and saliva, causing very dry eyes and mouth, plus tiredness and joint pain.

Main signsDry eyes and dry mouth
Common inWomen over 40
TreatmentMoisture, medicines

Overview

It can occur alone or with lupus or rheumatoid arthritis.

Dry mouth raises the risk of cavities, so dental care matters.

Symptoms

Common signs:

  • Dry eyes and dry mouth
  • Dry eyes and dry mouth together

Less common

  • Tiredness
  • Joint pain
  • Swollen glands by the jaw

When to get medical care

Call 911This isn't an emergency by itself. Call 911 for trouble breathing, chest pain, or fainting.
Get care todaySwollen glands that stay hard or grow.
See a doctor soonDryness affecting daily life.

Causes

Immune system attack on glands.

Does it spread or run in families?

  • It isn't contagious. You can't catch it from someone else.

Who is more likely to get it

  • Women
  • Other autoimmune diseases

Possible complications

Diagnosis

Blood tests and eye and mouth tests.

Questions you may be asked

  • Dryness, joint pain

The exam

Eye and mouth exam.

Tests

Tests, if needed:

  • Antibody tests:
  • Tear test:

Treatment

Keep eyes and mouth moist.

Self-care

  • Use artificial tears
  • Sip water and chew sugar-free gum
  • Use a humidifier
  • See a dentist every 6 months

Medicines

Medicines that may help:

MedicineHelps withGood to know
Saliva boosters
Dry mouthPrescription.
Immune medicines
Joint pain

OwieClear doesn't give doses: follow the label or your healthcare professional. Medicine names here are examples, not a full list.

Prevention

To protect teeth:

  • Fluoride toothpaste
  • Dental checkups

Which doctor treats this

  • Start with your primary care provider (family doctor or internist).
  • They may send you to a rheumatologist (joint and immune system doctor).

Pregnancy and breastfeeding

  • If you're pregnant or planning to be, tell your prenatal provider about this condition.
  • Don't start or stop any medicine on your own. Some are safe in pregnancy and some need to be changed.
  • Ask before taking any pain reliever. The FDA advises avoiding ibuprofen and naproxen after 20 weeks unless your doctor says to.
  • Breastfeeding: Most medicines are fine, but ask. The NIH LactMed database lists what's known about each one.

Outlook

Manageable.

Getting ready for your visit

Bring a list of your symptoms and medicines.

What to bring

  • A list of your medicines and supplements
  • Notes on when symptoms started and what makes them better or worse

Questions to ask

  • Do I have another immune condition too?

Research studies

Research studies test new ways to find and treat health problems. Some are looking for volunteers. Talk with your doctor before joining one.

Search ClinicalTrials.gov for studies on Sjögren's syndrome

Sources

Last updated 2026-11-12.