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Skin damage from radiation therapy

Also called: Radiation dermatitis, radiation skin burn, skin damage from radiation therapy

Redness, dryness, peeling, or open skin in the area treated with radiation. It usually starts after 2 to 3 weeks and heals a few weeks after treatment ends.

Starts2 to 3 weeks into treatment
Heals2 to 4 weeks after
TellYour radiation team

Overview

Skin folds like the armpit and under the breast are more likely to break down.

Symptoms

Common signs:

  • Red or peeling skin where radiation was given
  • Red, warm, swollen skin

Less common

  • Itching
  • Open, weepy skin

When to get medical care

Call 911This isn't an emergency by itself. Call 911 for trouble breathing, chest pain, or fainting.
Get care todayFever, pus, or spreading redness.
See a doctor soonOpen, painful, or worsening skin.

Causes

Radiation therapy.

Does it spread or run in families?

  • It isn't contagious. You can't catch it from someone else.

Who is more likely to get it

  • Skin folds
  • Higher doses

Diagnosis

Your radiation team checks your skin.

Treatment

Treat skin gently.

Self-care

  • Wash with mild soap and lukewarm water
  • Use the moisturizer your team recommends
  • Wear loose, soft clothing
  • Keep the area out of the sun
  • Don't use heat or ice packs

Medicines

Medicines that may help:

MedicineHelps withGood to know
Prescribed creams
Sore or broken skinAsk your team before using any product.

OwieClear doesn't give doses: follow the label or your healthcare professional. Medicine names here are examples, not a full list.

Which doctor treats this

  • Start with your primary care provider (family doctor or internist).
  • They may send you to a dermatologist (skin doctor).

Pregnancy and breastfeeding

  • If you're pregnant or planning to be, tell your prenatal provider about this condition.
  • Some skin medicines, like isotretinoin and retinoid creams, aren't safe in pregnancy.
  • Don't start or stop any medicine on your own. Some are safe in pregnancy and some need to be changed.
  • Ask before taking any pain reliever. The FDA advises avoiding ibuprofen and naproxen after 20 weeks unless your doctor says to.
  • Breastfeeding: Most medicines are fine, but ask. The NIH LactMed database lists what's known about each one.

Outlook

Usually heals.

Getting ready for your visit

Bring a list of your symptoms and medicines.

Questions to ask

  • What can I put on my skin?

Research studies

Research studies test new ways to find and treat health problems. Some are looking for volunteers. Talk with your doctor before joining one.

Search ClinicalTrials.gov for studies on Skin damage from radiation therapy

Sources

Last updated 2026-11-12.