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Yellow fever

Also called: Yellow fever

A mosquito-spread virus in parts of Africa and South America causing fever and, in severe cases, yellow skin and bleeding. A vaccine prevents it.

VaccineRequired for some countries

Overview

Most people get mild illness, but about 1 in 7 develop severe disease with liver damage.

Spread by mosquitoes in Africa and South America.

Skin and eyes may turn yellow.

Symptoms

Common signs:

  • Fever after travel

Less common

  • Yellow skin
  • Bleeding

When to get medical care

Call 911Yellow skin or bleeding.
Get care todayFever after travel.
See a doctor soonSymptoms that last or keep coming back.

Causes

Virus.

Does it spread or run in families?

  • It usually doesn't spread from person to person.
  • People get it from: mosquito bites.

Who is more likely to get it

  • Travelers

Diagnosis

A clinician asks about your symptoms and may order tests.

The exam

A physical exam.

Tests

Tests, if needed:

  • Blood tests:

Treatment

Treatment depends on the cause and how severe it is.

Self-care

  • Rest and fluids
  • Rest

Prevention

To lower your risk or catch problems early:

  • Vaccine before travel
  • Yellow fever vaccine

Which doctor treats this

  • Start with your primary care provider (family doctor or internist).
  • They may send you to an infectious disease specialist, for hard-to-treat infections.

Living with it

  • Keep a simple diary of symptoms, triggers, and medicines to bring to visits.
  • Bring a list of your medicines and questions to each visit.
  • Stay active in ways that feel good to you.
  • Get enough sleep and manage stress.
  • Long-term illness can affect mood. Tell your doctor if you feel down or anxious.

Back to school, work, or sports

  • Most people can keep working or going to school.
  • Ask about changes that help, like extra breaks or a flexible schedule. Workers may be covered by the ADA. Students may get a 504 plan.

Children, pregnancy, and older adults

  • Travelers: Check vaccine requirements.
  • Travelers: Need the vaccine.

Pregnancy and breastfeeding

  • If you're pregnant or planning to be, tell your prenatal provider about this condition.
  • Some infections can pass to the baby during pregnancy or birth. Tell your provider if you've been exposed.
  • Don't start or stop any medicine on your own. Some are safe in pregnancy and some need to be changed.
  • Ask before taking any pain reliever. The FDA advises avoiding ibuprofen and naproxen after 20 weeks unless your doctor says to.
  • Breastfeeding: Most medicines are fine, but ask. The NIH LactMed database lists what's known about each one.

For caregivers

  • Go to visits when you can and take notes.
  • Keep a list of medicines, allergies, and doctors in one place.
  • Learn the warning signs that need fast care.
  • Take breaks and ask for help. Caregivers need care too.

Outlook

One vaccine dose protects for life for most.

Most recover.

Getting ready for your visit

Bring a list of your symptoms and medicines.

What to bring

  • A list of your medicines and supplements
  • Notes on when symptoms started and what makes them better or worse

Questions to ask

  • What's causing this?
  • What treatment do you recommend?

Research studies

Research studies test new ways to find and treat health problems. Some are looking for volunteers. Talk with your doctor before joining one.

Search ClinicalTrials.gov for studies on Yellow fever

Sources

Last updated 2026-11-12.