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Acetazolamide

Brand names: Diamox (brand discontinued)

Acetazolamide helps prevent altitude sickness and treats glaucoma and pseudotumor cerebri (high brain pressure).

Brand namesDiamox (brand discontinued)
Type of medicineCarbonic anhydrase inhibitor
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It makes fizzy drinks taste flat and tingles the fingers.

What it's used for

  • Preventing and treating altitude sickness
  • Glaucoma
  • Pseudotumor cerebri
  • Some seizures

How to take it

  • For altitude, start the day before ascent.
  • Drink plenty of fluids.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Tingling fingers and toes
  • Peeing more
  • Altered taste
  • Tiredness
Call 911A blistering, peeling, or widespread red rash, especially with fever
Call your provider todaySide or back pain (kidney stone)
Call your provider todayUnusual bruising or fever with sore throat

Warnings

  • It's a sulfa-type medicine.
  • Descend if altitude sickness symptoms worsen.

Other medicines, foods, and alcohol

  • High-dose aspirin and topiramate add to side effects.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Talk with your provider.

Missed doses, overdose, and storage

If you miss a dose

Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.