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Amantadine

Brand names: Gocovri, Osmolex ER

Amantadine eases Parkinson's symptoms and the uncontrolled movements (dyskinesia) caused by levodopa.

Brand namesGocovri, Osmolex ER
Type of medicineParkinson's medicine (antiviral)
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It was once a flu medicine but isn't used for flu now because of resistance.

What it's used for

  • Parkinson's disease
  • Dyskinesia from levodopa
  • Movement side effects from some medicines

How to take it

  • Take it as prescribed; extended-release forms are taken at bedtime.
  • Don't stop suddenly.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Dizziness
  • Dry mouth
  • Swelling in the ankles
  • Mottled purple skin on the legs
  • Trouble sleeping
Call your provider todaySeeing things or confusion
Call your provider todayFalling asleep suddenly
Call 911Thoughts of suicide or harming yourself. Call or text 988 any time.

Warnings

  • Doses are lower with kidney disease.

Other medicines, foods, and alcohol

  • Alcohol adds to dizziness and confusion.
  • Anticholinergic medicines add to side effects.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Talk with your provider.

Missed doses, overdose, and storage

If you miss a dose

Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.