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Anastrozole

Brand names: Arimidex

Anastrozole lowers estrogen levels to treat hormone-sensitive breast cancer after menopause.

Brand namesArimidex
Type of medicineAromatase inhibitor (breast cancer medicine)
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It's often taken for 5 years or more after surgery.

What it's used for

  • Hormone-receptor-positive breast cancer after menopause

How to take it

  • Take it once a day at the same time, with or without food.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Hot flashes
  • Joint pain and stiffness
  • Tiredness
  • Bone thinning
Call 911Chest pain or shortness of breath
Call your provider todayA broken bone from a minor fall
Call 911A blistering, peeling, or widespread red rash, especially with fever

Warnings

  • Your provider will check bone density; calcium, vitamin D, or bone medicine may be added.

Other medicines, foods, and alcohol

  • Estrogen-containing medicines and tamoxifen work against it.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Not used in pregnancy.

Missed doses, overdose, and storage

If you miss a dose

Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.