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Benzoyl peroxide

Brand names: PanOxyl, Clearasil, Epiduo (with adapalene), Duac (with clindamycin)

Benzoyl peroxide kills acne bacteria and unclogs pores. It's in many acne washes, gels, and creams.

Brand namesPanOxyl, Clearasil, Epiduo (with adapalene), Duac (with clindamycin)
Type of medicineAcne medicine
Prescription?Over the counter (also in prescription combinations)
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

Bacteria don't become resistant to it, so it's often paired with antibiotic creams.

What it's used for

  • Acne

How to take it

  • Start once a day with a low strength, then increase if your skin tolerates it.
  • Washes: leave on for a minute or two, then rinse.
  • It bleaches towels, pillowcases, and clothing; use white fabrics.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Dryness, peeling, and redness
  • Mild burning
Call 911Swelling of the face, lips, or throat, or trouble breathing (rare)
Call your provider todaySevere burning, blistering, or swelling

Warnings

  • Use sunscreen and a moisturizer.
  • Keep it away from eyes, lips, and mouth.

Other medicines, foods, and alcohol

  • Using it at the same time as tretinoin can break down some forms of tretinoin; apply at different times.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Considered a reasonable acne option in pregnancy. Ask your provider.

Missed doses, overdose, and storage

If you miss a dose

Apply it when you remember, then go back to your usual schedule. Don't apply extra to make up for it.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.