Overview
Buprenorphine with naloxone (Suboxone) is used for opioid use disorder.
What it's used for
- Severe long-lasting pain
How to take it
- Patch: apply to clean skin and change every 7 days; avoid heat on the patch.
- Film: stick to the inside of the cheek.
- Keep naloxone (Narcan) at home and show family where it is. It can reverse an opioid overdose.
Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.
Side effects
Common side effects
- Nausea
- Headache
- Skin irritation (patch)
- Constipation
Warnings
- Boxed warnings: addiction, slowed breathing, and accidental exposure.
- It can affect heart rhythm, especially with other medicines that do the same.
Other medicines, foods, and alcohol
- Taking it with alcohol, benzodiazepines (like alprazolam or lorazepam), sleep medicines, gabapentin, or other opioids can slow breathing and cause death.
Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.
Pregnancy and breastfeeding
Talk with your provider.
Missed doses, overdose, and storage
If you miss a dose
Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.
If someone takes too much
Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.
Storing it
Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.
Conditions it's used for
Sources
- DailyMed: FDA drug label for Buprenorphine (patch and film for pain) (U.S. National Library of Medicine)
- MedlinePlus: Drugs, herbs, and supplements
- FDA: Drugs@FDA
Last updated 2026-11-13.