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Clobetasol

Brand names: Temovate, Clobex, Olux

Clobetasol is a very strong steroid cream, ointment, foam, or shampoo for stubborn psoriasis, eczema, and other inflamed skin.

Brand namesTemovate, Clobex, Olux
Type of medicineTopical steroid (very strong)
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It's one of the strongest topical steroids, so it's used for short periods on limited areas.

What it's used for

  • Psoriasis, including scalp psoriasis
  • Severe eczema
  • Other inflammatory skin conditions that haven't responded to milder creams

How to take it

  • Apply a thin layer once or twice a day, usually for no more than 2 weeks at a time.
  • Don't use it on the face, groin, or armpits unless your provider says to.
  • Don't cover with bandages unless told to. Wash hands after.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Burning or stinging
  • Dryness or itching
Call your provider todayThin, shiny skin, stretch marks, or easy bruising where used
Call your provider todayRash getting worse, oozing, or pus
Call your provider todayWeight gain, a round face, or high blood sugar with long use on large areas

Warnings

  • Not for children under 12 in most forms.
  • Don't use on ringworm, acne, or rosacea.

Other medicines, foods, and alcohol

  • Avoid using other steroid creams on the same area.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Use only on small areas for short periods, if at all. Ask your provider.

Missed doses, overdose, and storage

If you miss a dose

Apply it when you remember, then go back to your usual schedule. Don't apply extra to make up for it.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.