Overview
It's taken for 5 days each cycle. Twins are more likely.
What it's used for
- Helping ovulation in people with irregular or no ovulation, including PCOS
How to take it
- Take it for 5 days as your provider directs, usually starting on cycle day 3 to 5.
- Usually used for no more than 6 cycles.
Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.
Side effects
Common side effects
- Hot flashes
- Bloating
- Breast tenderness
- Mood swings
Warnings
- Not for people with ovarian cysts, liver disease, or abnormal uterine bleeding without a diagnosis.
Other medicines, foods, and alcohol
- Few interactions.
Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.
Pregnancy and breastfeeding
Stop it once pregnant; take a test before each cycle.
Missed doses, overdose, and storage
If you miss a dose
Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.
If someone takes too much
Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.
Storing it
Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.
Conditions it's used for
Sources
- DailyMed: FDA drug label for Clomiphene (U.S. National Library of Medicine)
- MedlinePlus: Drugs, herbs, and supplements
- FDA: Drugs@FDA
Last updated 2026-11-13.