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Docusate

Brand names: Colace, Dulcolax Stool Softener

Docusate is a stool softener that lets water mix into the stool, making it easier to pass.

Brand namesColace, Dulcolax Stool Softener
Type of medicineStool softener
Prescription?Over the counter
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It works best to prevent straining, such as after surgery or with hemorrhoids. It's a mild option.

What it's used for

  • Preventing hard stools and straining
  • After surgery or childbirth

How to take it

  • Take it with a full glass of water.
  • It usually works in 1 to 3 days.
  • Don't use it longer than 1 week unless a provider says to.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Mild cramps
  • Throat irritation (liquid)
Call your provider todayBleeding from the rectum
Call your provider todayNo bowel movement after using a laxative

Warnings

  • See a provider for a sudden change in bowel habits lasting 2 weeks, or for belly pain, nausea, or vomiting.

Other medicines, foods, and alcohol

  • Don't take with mineral oil.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Commonly used in pregnancy. Ask your provider.

Missed doses, overdose, and storage

If you miss a dose

This medicine is often taken only when needed. If you take it on a schedule, take a missed dose when you remember, unless it's almost time for the next one. Don't double up.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.