ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.
Overview
It works on brain temperature control.
What it's used for
- Hot flashes and night sweats from menopause
How to take it
- Take it once a day.
- Liver blood tests are checked before and during the first months.
Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.
Side effects
Common side effects
- Belly pain
- Diarrhea
- Trouble sleeping
- Back pain
Call your provider todayYellow skin or eyes, dark urine, or pain in the upper right belly
Call your provider todayUnusual tiredness, nausea, or itching
Warnings
- Boxed warning: liver injury.
Other medicines, foods, and alcohol
- Never take with CYP1A2 blockers like fluvoxamine or ciprofloxacin.
Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.
Pregnancy and breastfeeding
Not used in pregnancy.
Missed doses, overdose, and storage
If you miss a dose
Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.
If someone takes too much
Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.
Storing it
Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.
Conditions it's used for
Sources
- DailyMed: FDA drug label for Fezolinetant (U.S. National Library of Medicine)
- MedlinePlus: Drugs, herbs, and supplements
- FDA: Drugs@FDA
Last updated 2026-11-13.