Overview
It's often taken with hydrocortisone in adrenal insufficiency.
What it's used for
- Addison's disease (with hydrocortisone)
- Off-label: dizziness when standing (orthostatic hypotension) and POTS
How to take it
- Take it once a day.
- Your provider may suggest more salt in your diet.
Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.
Side effects
Common side effects
- Swelling
- Headache
- Low potassium
Warnings
- Blood pressure and potassium are checked.
Other medicines, foods, and alcohol
- Water pills add to potassium loss.
Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.
Pregnancy and breastfeeding
Talk with your provider.
Missed doses, overdose, and storage
If you miss a dose
Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.
If someone takes too much
Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.
Storing it
Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.
Conditions it's used for
Sources
- DailyMed: FDA drug label for Fludrocortisone (U.S. National Library of Medicine)
- MedlinePlus: Drugs, herbs, and supplements
- FDA: Drugs@FDA
Last updated 2026-11-13.