Overview
Everyone who could become pregnant is advised to take it daily, starting before pregnancy.
What it's used for
- Preventing neural tube defects before and during early pregnancy
- Folate deficiency anemia
- With methotrexate to lower side effects
How to take it
- Take it once a day, with or without food.
- With methotrexate, follow your provider's schedule.
Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.
Side effects
Common side effects
- Usually none
Warnings
- Folic acid can hide B12 deficiency; your provider may check B12.
Other medicines, foods, and alcohol
- It may lower levels of phenytoin and some other seizure medicines.
Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.
Pregnancy and breastfeeding
Recommended for everyone who could become pregnant. Your provider may advise a higher dose in some cases.
Missed doses, overdose, and storage
If you miss a dose
Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.
If someone takes too much
Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.
Storing it
Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.
Conditions it's used for
Sources
- DailyMed: FDA drug label for Folic acid (U.S. National Library of Medicine)
- MedlinePlus: Drugs, herbs, and supplements
- FDA: Drugs@FDA
Last updated 2026-11-13.