Overview
Drinking plenty of fluids helps it work. Many combination products also contain other medicines.
What it's used for
- Chest congestion from colds and bronchitis
How to take it
- Take it with a full glass of water.
- Swallow extended-release tablets whole.
- Check labels so you don't double up on other ingredients.
- Don't give cough and cold medicines to children under 4.
Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.
Side effects
Common side effects
- Nausea
- Dizziness
- Headache
Warnings
- Ask a provider for a cough from smoking, asthma, or COPD, or with lots of mucus.
Other medicines, foods, and alcohol
- Few interactions on its own; check other ingredients in combination products.
Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.
Pregnancy and breastfeeding
Ask your provider before using it in pregnancy.
Missed doses, overdose, and storage
If you miss a dose
This medicine is often taken only when needed. If you take it on a schedule, take a missed dose when you remember, unless it's almost time for the next one. Don't double up.
If someone takes too much
Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.
Storing it
Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.
Conditions it's used for
Sources
- DailyMed: FDA drug label for Guaifenesin (U.S. National Library of Medicine)
- MedlinePlus: Drugs, herbs, and supplements
- FDA: Drugs@FDA
Last updated 2026-11-13.