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Hydralazine

Brand names: BiDil (with isosorbide dinitrate)

Hydralazine relaxes the arteries to lower blood pressure. With a nitrate, it also treats heart failure.

Brand namesBiDil (with isosorbide dinitrate)
Type of medicineVasodilator (blood pressure medicine)
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It's usually added to other blood pressure medicines. It's also used in pregnancy.

What it's used for

  • High blood pressure
  • Heart failure (with isosorbide dinitrate)
  • Severe high blood pressure in pregnancy (by shot)

How to take it

  • Take it with food at the same times each day, usually several times a day.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Headache
  • Fast heartbeat
  • Flushing
  • Nausea
  • Swelling
Call 911Chest pain
Call your provider todayJoint pain, fever, rash, and tiredness together (rare lupus-like reaction)
Call your provider todayNumbness or tingling in hands or feet

Warnings

  • Your provider may check blood tests if you take it long term.

Other medicines, foods, and alcohol

  • Other blood pressure medicines add to its effect.
  • Beta blockers are often given with it to control a fast heartbeat.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Used to treat high blood pressure in pregnancy.

Missed doses, overdose, and storage

If you miss a dose

Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.