ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.
Overview
Blood counts are checked regularly.
What it's used for
- Sickle cell disease
- Polycythemia vera and some other blood disorders
- Some cancers
How to take it
- Take it once a day.
- Wash hands after handling capsules; caregivers should wear gloves.
- Keep all blood test appointments.
Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.
Side effects
Common side effects
- Low blood counts
- Darkening of skin and nails
- Nausea
Call your provider todayFever, chills, sore throat, or other signs of infection
Call your provider todayUnusual bruising or bleeding
Call your provider todayLeg ulcers
Warnings
- It can harm an unborn baby; use birth control during and after treatment.
Other medicines, foods, and alcohol
- Live vaccines should be avoided.
Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.
Pregnancy and breastfeeding
Not used in pregnancy.
Missed doses, overdose, and storage
If you miss a dose
Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.
If someone takes too much
Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.
Storing it
Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.
Conditions it's used for
Sources
- DailyMed: FDA drug label for Hydroxyurea (U.S. National Library of Medicine)
- MedlinePlus: Drugs, herbs, and supplements
- FDA: Drugs@FDA
Last updated 2026-11-13.