ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.
Overview
Overdose is very dangerous.
What it's used for
- Depression
- Bedwetting in children 6 and older
How to take it
- Take it as prescribed. Don't stop suddenly.
- Keep it locked up.
Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.
Side effects
Common side effects
- Dry mouth
- Constipation
- Sleepiness
- Dizziness
Call 911Thoughts of suicide or harming yourself. Call or text 988 any time.
Call 911Fainting or a fast, irregular heartbeat
Call your provider todayTrouble peeing or confusion
Warnings
- Children, teens, and young adults can have more suicidal thoughts when starting. Watch closely in the first weeks.
- Overdose can quickly affect the heart.
Other medicines, foods, and alcohol
- Never take within 14 days of an MAOI.
- Fluoxetine, paroxetine, and bupropion raise its level.
Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.
Pregnancy and breastfeeding
Talk with your provider.
Missed doses, overdose, and storage
If you miss a dose
Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.
If someone takes too much
An overdose is an emergency that can quickly affect the heart. Call 911 right away. You can also call Poison Control at 1-800-222-1222.
Storing it
Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.
Conditions it's used for
Sources
- DailyMed: FDA drug label for Imipramine (U.S. National Library of Medicine)
- MedlinePlus: Drugs, herbs, and supplements
- FDA: Drugs@FDA
Last updated 2026-11-13.