ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.
Overview
It lowers LDL by about half by turning down a liver protein.
What it's used for
- High LDL cholesterol with or without heart disease
How to take it
- Given in a clinic: first dose, again at 3 months, then every 6 months.
Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.
Side effects
Common side effects
- Injection site reactions
- Joint pain
Call 911Swelling of the face, lips, or throat, hives, or trouble breathing
Warnings
- Used with diet and often a statin.
Other medicines, foods, and alcohol
- Few interactions.
Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.
Pregnancy and breastfeeding
Talk with your provider.
Missed doses, overdose, and storage
If you miss a dose
Schedule the shot as soon as possible; your provider will reset your schedule.
If someone takes too much
Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.
Storing it
Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.
Conditions it's used for
Sources
- DailyMed: FDA drug label for Inclisiran (U.S. National Library of Medicine)
- MedlinePlus: Drugs, herbs, and supplements
- FDA: Drugs@FDA
Last updated 2026-11-13.