Overview
It acts faster and wears off sooner than levothyroxine.
What it's used for
- Underactive thyroid (usually with levothyroxine)
- Thyroid testing and some thyroid cancer care
How to take it
- Take it at the same time each day.
- Separate it from calcium, iron, and antacids by 4 hours.
Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.
Side effects
Common side effects
- Fast heartbeat
- Nervousness
- Trouble sleeping
- Sweating
Warnings
- Boxed warning: not for weight loss; large doses can be dangerous.
Other medicines, foods, and alcohol
- Calcium, iron, and antacids lower absorption.
- Blood thinners may need monitoring.
Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.
Pregnancy and breastfeeding
Talk with your provider; thyroid needs change in pregnancy.
Missed doses, overdose, and storage
If you miss a dose
Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.
If someone takes too much
Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.
Storing it
Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.
Conditions it's used for
Sources
- DailyMed: FDA drug label for Liothyronine (U.S. National Library of Medicine)
- MedlinePlus: Drugs, herbs, and supplements
- FDA: Drugs@FDA
Last updated 2026-11-13.