Memantine

Overview

It's often taken with donepezil. It doesn't stop the disease.

What it's used for

• Moderate to severe Alzheimer's dementia

How to take it

• Take it with or without food. The dose is raised slowly over weeks.
• Extended-release capsules can be opened and sprinkled on applesauce.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

• Dizziness
• Headache
• Confusion
• Constipation

Warnings

• Doses are lower with kidney disease.

Other medicines, foods, and alcohol

• Things that make urine less acidic (like sodium bicarbonate or a big diet change) can raise its level.
• Amantadine and dextromethorphan may add side effects.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Not usually relevant; ask your provider.

Missed doses, overdose, and storage

If you miss a dose

Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

• Memory loss and dementia