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Methyldopa

Brand names: Aldomet (brand discontinued)

Methyldopa lowers blood pressure by acting on the brain. It's mostly used for high blood pressure during pregnancy.

Brand namesAldomet (brand discontinued)
Type of medicineCentral alpha agonist (blood pressure medicine)
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It's one of the most studied blood pressure medicines in pregnancy.

What it's used for

  • High blood pressure, especially in pregnancy

How to take it

  • Take it the same way each day.
  • Don't stop suddenly.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Sleepiness
  • Dizziness
  • Dry mouth
  • Headache
Call your provider todayYellow skin or eyes or dark urine
Call your provider todayUnusual tiredness or pale skin (rare red cell breakdown)
Call your provider todayFever

Warnings

  • Blood tests may be checked during long-term use.

Other medicines, foods, and alcohol

  • Iron supplements can lower its effect.
  • Lithium levels may rise.
  • Never take within 14 days of an MAOI.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Commonly used for high blood pressure in pregnancy.

Missed doses, overdose, and storage

If you miss a dose

Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.