Health information to help you understand symptoms. It isn't a diagnosis.
Check symptoms

Mirtazapine

Brand names: Remeron, RemeronSolTab

Mirtazapine is an antidepressant that also helps with sleep and appetite.

Brand namesRemeron, RemeronSolTab
Type of medicineAntidepressant (NaSSA)
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It's taken at bedtime because it's sedating. It often increases appetite and weight.

What it's used for

  • Depression

How to take it

  • Take it at bedtime.
  • Dissolving tablets melt on the tongue.
  • Don't stop suddenly.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Sleepiness
  • More appetite and weight gain
  • Dry mouth
  • Constipation
  • Dizziness
Call 911Thoughts of suicide or harming yourself. Call or text 988 any time.
Call 911Agitation, fever, sweating, muscle twitching or stiffness, fast heartbeat, and confusion (possible serotonin syndrome)
Call 911Fever, sore throat, or mouth sores (possible low white blood cells)
Call 911A blistering, peeling, or widespread red rash, especially with fever

Warnings

  • Children, teens, and young adults can have more suicidal thoughts when starting.
  • Don't drive until you know how it affects you.

Other medicines, foods, and alcohol

  • Never take within 14 days of an MAOI.
  • Alcohol and sedating medicines add to drowsiness.
  • Other serotonin medicines raise the risk of serotonin syndrome.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Talk with your provider about benefits and risks.

Missed doses, overdose, and storage

If you miss a dose

Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.