Overview
Fast-acting forms treat an attack; patches and ointment help prevent attacks.
What it's used for
- Relieving an angina attack
- Preventing angina before activity
- Preventing angina (patches)
How to take it
- At the first sign of chest pain, sit down and use one dose under the tongue or one spray.
- If pain isn't better or is worse 5 minutes after the first dose, call 911 right away.
- Keep tablets in their original glass bottle, tightly closed, and replace before the expiration date.
- Remove patches for 10 to 14 hours each day as directed so they keep working.
Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.
Side effects
Common side effects
- Headache
- Flushing
- Dizziness or lightheadedness
Warnings
- Sit down before using it; it can make you dizzy.
Other medicines, foods, and alcohol
- Never take with erectile dysfunction medicines (sildenafil, tadalafil, vardenafil) or riociguat. Blood pressure can drop dangerously.
- Alcohol and blood pressure medicines add to dizziness.
Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.
Pregnancy and breastfeeding
Talk with your provider.
Missed doses, overdose, and storage
If you miss a dose
This medicine is often taken only when needed. If you take it on a schedule, take a missed dose when you remember, unless it's almost time for the next one. Don't double up.
If someone takes too much
Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.
Storing it
Keep tablets in their original glass bottle with the cap tight, at room temperature. Carry them with you, but not in a pocket against your body.
Conditions it's used for
Sources
- DailyMed: FDA drug label for Nitroglycerin (U.S. National Library of Medicine)
- MedlinePlus: Drugs, herbs, and supplements
- FDA: Drugs@FDA
Last updated 2026-11-13.