Overview
Rebound congestion (rhinitis medicamentosa) makes people feel they can't stop using it.
What it's used for
- Short-term stuffy nose from colds, allergies, or sinus infections
- Nosebleeds (in clinics)
How to take it
- Use no more than twice a day and no longer than 3 days.
- Don't share the bottle.
Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.
Side effects
Common side effects
- Burning or stinging
- Sneezing
- Rebound stuffiness
Warnings
- Not for children under 6 unless a provider says to.
Other medicines, foods, and alcohol
- Never take within 14 days of an MAOI.
Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.
Pregnancy and breastfeeding
Ask your provider.
Missed doses, overdose, and storage
If you miss a dose
This medicine is often taken only when needed. If you take it on a schedule, take a missed dose when you remember, unless it's almost time for the next one. Don't double up.
If someone takes too much
Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.
Storing it
Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.
Conditions it's used for
Sources
- DailyMed: FDA drug label for Oxymetazoline nasal spray (U.S. National Library of Medicine)
- MedlinePlus: Drugs, herbs, and supplements
- FDA: Drugs@FDA
Last updated 2026-11-13.