ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.
Overview
For restless legs, it's taken 2 to 3 hours before bedtime.
What it's used for
- Parkinson's disease
- Restless legs syndrome
How to take it
- Take it with food if it causes nausea.
- Don't stop suddenly.
Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.
Side effects
Common side effects
- Nausea
- Sleepiness
- Dizziness
- Swelling
Call 911Falling asleep suddenly during activities like driving
Call your provider todayStrong urges you can't control, like gambling or shopping
Call your provider todaySeeing things
Call your provider todayRestless legs getting worse or starting earlier in the day
Warnings
- Doses are lower with kidney disease.
- Have your skin checked; Parkinson's raises melanoma risk.
Other medicines, foods, and alcohol
- Antipsychotics and metoclopramide work against it.
- Alcohol and sedating medicines add to sleepiness.
Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.
Pregnancy and breastfeeding
Talk with your provider.
Missed doses, overdose, and storage
If you miss a dose
Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.
If someone takes too much
Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.
Storing it
Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.
Conditions it's used for
Sources
- DailyMed: FDA drug label for Pramipexole (U.S. National Library of Medicine)
- MedlinePlus: Drugs, herbs, and supplements
- FDA: Drugs@FDA
Last updated 2026-11-13.