Overview
It's started at a very low dose because first doses can cause strong drowsiness and unsteadiness.
What it's used for
- Essential tremor (off-label but common)
- Seizures
How to take it
- Take it at bedtime at first.
- Don't stop suddenly.
Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.
Side effects
Common side effects
- Sleepiness
- Unsteadiness
- Dizziness
- Nausea
Warnings
- It makes hormonal birth control less effective.
Other medicines, foods, and alcohol
- Alcohol and sedating medicines add to drowsiness.
- It lowers levels of many medicines, including warfarin and birth control.
Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.
Pregnancy and breastfeeding
Talk with your provider before pregnancy.
Missed doses, overdose, and storage
If you miss a dose
Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.
If someone takes too much
Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.
Storing it
Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.
Conditions it's used for
Sources
- DailyMed: FDA drug label for Primidone (U.S. National Library of Medicine)
- MedlinePlus: Drugs, herbs, and supplements
- FDA: Drugs@FDA
Last updated 2026-11-13.