Overview
Effects last a few hours, so doses are timed around activities and meals.
What it's used for
- Myasthenia gravis
- Off-label: dizziness when standing and POTS
How to take it
- Take it as prescribed, often 30 to 60 minutes before meals.
Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.
Side effects
Common side effects
- Stomach cramps
- Diarrhea
- Sweating
- Muscle twitching
Warnings
- Too much can cause weakness similar to the disease.
Other medicines, foods, and alcohol
- Some antibiotics and beta blockers can worsen myasthenia.
Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.
Pregnancy and breastfeeding
Talk with your provider.
Missed doses, overdose, and storage
If you miss a dose
Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.
If someone takes too much
Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.
Storing it
Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.
Conditions it's used for
Sources
- DailyMed: FDA drug label for Pyridostigmine (U.S. National Library of Medicine)
- MedlinePlus: Drugs, herbs, and supplements
- FDA: Drugs@FDA
Last updated 2026-11-13.