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Quinapril

Brand names: Accupril, Accuretic (with HCTZ)

Quinapril is an ACE inhibitor that relaxes blood vessels to lower blood pressure and protect the heart and kidneys.

Brand namesAccupril, Accuretic (with HCTZ)
Type of medicineACE inhibitor (blood pressure medicine)
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It blocks a hormone that tightens blood vessels, which lowers blood pressure and eases the heart's work.

A dry cough is a common reason people switch to an ARB.

What it's used for

  • High blood pressure
  • Heart failure

How to take it

  • Take it at the same time each day, with or without food.
  • Keep taking it even if you feel well.
  • Stand up slowly at first.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Dry, tickly cough
  • Dizziness
  • Headache
  • Tiredness
Call 911Swelling of the face, lips, tongue, or throat, or trouble breathing (can happen even after years of use)
Call your provider todayFainting or severe dizziness
Call your provider todayMuscle weakness or a slow or irregular heartbeat (possible high potassium)
Call your provider todayPeeing much less than usual

Warnings

  • Do not take during pregnancy; it can harm an unborn baby.
  • Your provider will check kidney function and potassium.
  • Not for people who've had swelling (angioedema) from an ACE inhibitor.

Other medicines, foods, and alcohol

  • Potassium supplements, salt substitutes, and potassium-sparing water pills can raise potassium too high.
  • NSAIDs like ibuprofen and naproxen can weaken its effect and strain the kidneys.
  • Lithium levels can rise.
  • Don't take with sacubitril-valsartan (Entresto).

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Don't take it if you are pregnant. If you become pregnant, call your provider right away to switch medicines.

Missed doses, overdose, and storage

If you miss a dose

Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.