Raloxifene

Overview

It acts like estrogen in bone but blocks estrogen in the breast and uterus.

What it's used for

• Osteoporosis after menopause
• Lowering breast cancer risk after menopause

How to take it

• Take it once a day, with or without food.
• Stop it at least 72 hours before long periods of not moving (like surgery or long trips).

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

• Hot flashes
• Leg cramps
• Swelling
• Joint pain

Warnings

• Boxed warning: blood clots and death from stroke in women with heart disease risk.

Other medicines, foods, and alcohol

• Cholestyramine blocks absorption.
• It can change warfarin's effect.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Not used in pregnancy.

Missed doses, overdose, and storage

If you miss a dose

Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

• Osteoporosis (bone loss)
• Breast cancer (needs checking)