Overview
It doesn't lower heart rate or blood pressure much. It doesn't stop an attack in progress.
What it's used for
- Chronic angina
How to take it
- Swallow tablets whole twice a day, with or without food.
Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.
Side effects
Common side effects
- Dizziness
- Headache
- Constipation
- Nausea
Warnings
- It can affect heart rhythm.
- Not for people with liver cirrhosis.
Other medicines, foods, and alcohol
- Never take with strong drugs that raise its level (ketoconazole, clarithromycin, ritonavir) or lower it (rifampin, St. John's wort).
- It raises simvastatin, metformin, and digoxin levels.
- Avoid grapefruit juice.
Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.
Pregnancy and breastfeeding
Talk with your provider.
Missed doses, overdose, and storage
If you miss a dose
Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.
If someone takes too much
Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.
Storing it
Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.
Conditions it's used for
Sources
- DailyMed: FDA drug label for Ranolazine (U.S. National Library of Medicine)
- MedlinePlus: Drugs, herbs, and supplements
- FDA: Drugs@FDA
Last updated 2026-11-13.