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Rasagiline

Brand names: Azilect

Rasagiline treats Parkinson's symptoms alone or added to levodopa.

Brand namesAzilect
Type of medicineMAO-B inhibitor (Parkinson's medicine)
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It's taken once a day.

What it's used for

  • Parkinson's disease

How to take it

  • Take it once a day, with or without food.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Headache
  • Joint pain
  • Indigestion
Call 911Very high blood pressure: severe headache, chest pain, or confusion
Call 911Agitation, fever, sweating, muscle twitching or stiffness, fast heartbeat, and confusion (possible serotonin syndrome)
Call your provider todayFalling asleep suddenly or strong urges you can't control

Warnings

  • Have skin checked for melanoma.

Other medicines, foods, and alcohol

  • Never combine with meperidine, tramadol, methadone, dextromethorphan, St. John's wort, or other MAOIs.
  • Antidepressants need caution.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Talk with your provider.

Missed doses, overdose, and storage

If you miss a dose

Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.