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Repaglinide

Brand names: Prandin (brand discontinued)

Repaglinide is a fast, short-acting pill taken before meals to lower blood sugar in type 2 diabetes.

Brand namesPrandin (brand discontinued)
Type of medicineMeglitinide (diabetes medicine)
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

If you skip a meal, you skip the dose.

What it's used for

  • Type 2 diabetes

How to take it

  • Take it up to 30 minutes before each meal; skip the dose if you skip the meal.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Low blood sugar
  • Headache
  • Upper respiratory infection
Call 911Severe low blood sugar: confusion, seizure, or passing out

Warnings

  • Not for type 1 diabetes.

Other medicines, foods, and alcohol

  • Never take with gemfibrozil.
  • Clopidogrel and some antifungals raise its level.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Insulin is usually preferred in pregnancy.

Missed doses, overdose, and storage

If you miss a dose

Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.