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Risankizumab

Brand names: Skyrizi

Risankizumab is a biologic for psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis, given every 8 to 12 weeks after starter doses.

Brand namesSkyrizi
Type of medicineBiologic (IL-23 blocker)
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

Some starter doses are given by IV.

What it's used for

  • Psoriasis
  • Psoriatic arthritis
  • Crohn's disease
  • Ulcerative colitis

How to take it

  • Inject under the skin as scheduled.
  • You'll be tested for TB and hepatitis B before starting. Avoid live vaccines.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Colds
  • Headache
  • Tiredness
Call your provider todayFever, chills, sore throat, or other signs of infection
Call your provider todayYellow skin or eyes, dark urine, or pain in the upper right belly

Warnings

  • Liver tests are checked in Crohn's and colitis treatment.

Other medicines, foods, and alcohol

  • Few interactions.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Talk with your provider.

Missed doses, overdose, and storage

If you miss a dose

Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.