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Salicylic acid (skin)

Brand names: Compound W, Clearasil, Stridex, Duofilm

Salicylic acid unclogs pores and dissolves thick skin. It treats acne, warts, corns, and calluses.

Brand namesCompound W, Clearasil, Stridex, Duofilm
Type of medicineKeratolytic (wart and acne treatment)
Prescription?Over the counter
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

Strength varies a lot between products.

What it's used for

  • Acne
  • Common and plantar warts
  • Corns and calluses
  • Scaly scalp

How to take it

  • For warts: soak, file the dead skin, then apply daily for weeks.
  • Don't use wart products on the face, genitals, moles, or irritated skin.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Dryness
  • Peeling
  • Stinging
Call your provider todaySevere redness, blistering, or open sores

Warnings

  • People with diabetes or poor circulation should ask before treating feet.

Other medicines, foods, and alcohol

  • Avoid other drying products on the same area.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Small areas are generally OK. Ask your provider.

Missed doses, overdose, and storage

If you miss a dose

Apply it when you remember, then go back to your usual schedule. Don't apply extra to make up for it.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.