Sofosbuvir and velpatasvir

Overview

Cure rates are over 95%. You'll be tested for hepatitis B first.

What it's used for

• Hepatitis C

How to take it

• Take one tablet daily for 12 weeks without missing doses.
• Tell your provider about every medicine and supplement.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

• Headache
• Tiredness
• Nausea

Warnings

• Boxed warning: hepatitis B can flare during or after treatment in people with both infections.

Other medicines, foods, and alcohol

• Never combine with amiodarone.
• PPIs, H2 blockers, and antacids lower absorption; timing rules apply.
• Rifampin, St. John's wort, and some seizure medicines make it fail.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Talk with your provider.

Missed doses, overdose, and storage

If you miss a dose

Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

• Hepatitis C