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Sotalol

Brand names: Betapace, Sotylize

Sotalol keeps the heart in a normal rhythm in people with atrial fibrillation and some dangerous rhythm problems.

Brand namesBetapace, Sotylize
Type of medicineAntiarrhythmic (heart rhythm medicine)
Prescription?Prescription
ImportantThis page is general information, not a prescription. Don't start, stop, or change a medicine without talking to your provider or pharmacist.

Overview

It's started in a hospital or monitored setting because it can cause dangerous rhythms.

What it's used for

  • Keeping a normal rhythm in atrial fibrillation or flutter
  • Some life-threatening fast rhythms

How to take it

  • Take it at the same times each day.
  • Don't switch brands; Betapace AF and Betapace aren't interchangeable.
  • Don't stop suddenly.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

  • Tiredness
  • Slow heartbeat
  • Dizziness
  • Shortness of breath
Call 911Fainting, a fast or irregular heartbeat, or chest pain
Call your provider todaySevere diarrhea or vomiting (can change salts and raise rhythm risk)

Warnings

  • Boxed warning: start in a facility with heart monitoring for at least 3 days.
  • Doses depend on kidney function.

Other medicines, foods, and alcohol

  • Many medicines that affect heart rhythm add to the risk.
  • Antacids lower absorption; separate by 2 hours.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Talk with your provider.

Missed doses, overdose, and storage

If you miss a dose

Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

Sources

Last updated 2026-11-13.