Spironolactone

Overview

It blocks the hormone aldosterone. It also blocks some effects of male hormones.

What it's used for

• Heart failure
• High blood pressure that's hard to control
• Fluid buildup from liver disease or kidney problems
• Too much aldosterone
• Off-label: acne and hair loss in women

How to take it

• Take it with or without food, the same way each day.
• Take it in the morning if you pee more.

Your dose depends on your health and other medicines. Always follow your prescription label, and ask your pharmacist if anything is unclear.

Side effects

Common side effects

• Breast swelling or tenderness
• Irregular periods
• Dizziness
• Peeing more

Warnings

• Your provider will check potassium and kidney function.
• Avoid it if you have high potassium or serious kidney problems.

Other medicines, foods, and alcohol

• Potassium supplements, salt substitutes, ACE inhibitors, ARBs, and trimethoprim can raise potassium too high.
• NSAIDs weaken its effect and raise potassium.
• Lithium levels can rise.

Tell your provider and pharmacist about every medicine, vitamin, and supplement you take.

Pregnancy and breastfeeding

Not usually used in pregnancy. Talk with your provider.

Missed doses, overdose, and storage

If you miss a dose

Take it as soon as you remember, unless it's almost time for your next dose. Then skip the missed dose. Don't take two doses at once.

If someone takes too much

Call Poison Control at 1-800-222-1222 or get help online at poison.org. Call 911 if the person collapses, has a seizure, has trouble breathing, or can't be woken.

Storing it

Store at room temperature, away from heat and moisture (not in the bathroom), and out of reach of children and pets.

Conditions it's used for

• Heart failure
• High blood pressure (hypertension)
• Acne
• Pattern hair loss (male or female pattern)