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Sore throat or ear pain on one side that won't go away, or a lump on the tongue

Also called: Persistent one-sided throat pain

A one-sided sore throat or ear pain that won't go away, or a lump on the tongue, should be checked for head and neck cancer.

Common causesSeveral causes, including cancer
Usually serious?Needs evaluation
Get checked ifAlways
If you think it's an emergency, call 911.Thinking about suicide? Call or text 988.

Overview

Tobacco, alcohol, and HPV raise risk.

Lasting over 3 weeks needs checking.

When to get medical care

Call 911Not an emergency.
Get care todayBleeding, severe pain, or trouble breathing or swallowing.
See a doctor soonMake an appointment soon; don't wait.

Causes

Causes include infections and head and neck cancer.

OwieClear has pages on 3 conditions that can cause sore throat or ear pain on one side that won't go away, or a lump on the tongue. Each shows how soon to get care.

Common causes

What you can do at home

  • Keep all follow-up appointments.
  • Write down your questions.

Medicines

Treatment depends on what tests find.

At the doctor

Tests will look for the cause.

Questions you may be asked

  • How long
  • Weight loss
  • Smoking and family history

The exam

A physical exam.

Tests

  • Scope exam
  • Biopsy

Prevention

Lower your risk.

  • Don't smoke
  • Get recommended screenings

Check your symptoms

Most symptoms have more than one possible cause. The symptom checker looks at all of your symptoms together, plus your age, and shows how soon to get care.

Start the symptom checker

Sources

Last updated 2026-11-13.