Good to knowOne result rarely tells the whole story. Your provider looks at your results together with your symptoms, exam, and other tests.
What the test is
Your provider may ask you to hold steroid medicines beforehand.
Why it's done
- Low morning cortisol
- Weakness, weight loss, low blood pressure, or salt craving
Getting ready and what happens
- Follow instructions about steroid medicines and timing.
How the test is done
- Blood is drawn, a synthetic ACTH shot is given, and blood is drawn again after 30 and/or 60 minutes.
What the results mean
Cortisol rises well
Adrenal insufficiency is unlikely.
Cortisol doesn't rise enough
Supports adrenal insufficiency, treated with steroid replacement.
Questions to ask your provider
- What do my results mean for me?
- Do I need to repeat this test or have other tests?
Risks
A blood draw is very safe. You may have slight pain or a small bruise where the needle went in.
Related conditions
Related medicines
Related tests
Sources
Last updated 2026-11-13.